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Induction of suppressor cells in normal lymphocytes by uremic serum
International Archives of Allergy and Applied Immunology
|January 1, 1986
Abstract:
Sera of patients on chronic hemodialysis induced suppressor cell activity (SCA) in normal peripheral blood mononuclear cells, which significantly impaired blastogenic response to PHA. This SCA is statistically not different from Con A induced SCA. Both SCAs are however additive. Speculations concerning the modes of action of this induced SCA are discussed.