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Updated: Feb 14, 2026

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications
Published on: February 6, 2016
Effects of CdSe and CdSe/ZnS Core/Shell Quantum Dots on Singlet Oxygen Production and Cell Toxicity
Hong Dinh Duong1, Sumin Yang1, Young Woo Seo2
1School of Chemical Engineering, Chonnam National University, Yong-Bong Ro 77, 61186 Gwangju, Republic of Korea.
Abstract:
Four types of quantum dots (QDs) with varying emission wavelengths were synthesized in this study. The dots included CdSe and CdSe/ZnS core/shell QDs with short emission wavelengths of 540 nm and 560 nm, respectively, as well as CdSe and CdSe/ZnS core/shell QDs with longer emission wavelengths of 585 nm and 595 nm, respectively. The ligands on the QD surfaces were exchanged with mercaptopropionic acid (MPA) to make them water-soluble. The efficiency of singlet oxygen (1O2) production from both CdSe and CdSe/ZnS core/shell QDs was highest at a QD concentration of 14 μg/ml Singlet oxygen production from the CdSe QDs was higher than that with the CdSe/ZnS core/shell QDs after 1 h of LED470 irradiation. However, the singlet oxygen production of CdSe/ZnS core/shell QDs was much higher than that of CdSe QDs at concentrations above 14 μg/ml. The cytotoxicities of both CdSe and CdSe/ZnS core/shell QDs were investigated using HeLa cells.
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