Related Experiment Video
Updated: Feb 14, 2026

Mechanical Micronization of Lipoaspirates for Regenerative Therapy
Published on: March 15, 2019
Matrix regenerative therapy
Cristina-Mihaela Timaru1, Cornel Stefan1, Daniela Adriana Iliescu1
1phthalmology Department, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.
Abstract:
The extracellular matrix (ECM) is responsible for many of the cell behavior processes, including cell proliferation and growth, survival, change in cell shape, migration, and differentiation. The most important component of the ECM is heparan sulfate (HS), because it insures the storage of many cell communication proteins, necessary for the continuous and identical renewal of cells and thus for tissue regeneration. Regenerating agents (RGTA®) are bioengineered structural analogues of heparan sulfate glycosaminoglycans that replace the degraded endogenous HS of the ECM. In the ophthalmological field, RGTA® represents an innovative approach for the improvement of the ocular surface wound healing and matrix remodeling and plays a role in controlling and regulating the wound healing process in various ocular diseases.
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