Surgical Management of Complicated Chronic Uveitis: A Case Report

Chronic uveitis is a common vision-threatening condition that can lead to many complications and may not respond to conventional medical therapy. This case report aims to emphasize the need for a personalized approach to these challenging cases to reestablish visual function.

A 29-year-old female patient, C.F., developed bilateral anterior uveitis of unknown origin that evolved into a chronic, refractory form. Topical, as well as systemic therapy, failed to control the inflammation, leading to complications in the form of cataract and secondary glaucoma. Surgical management involved Ahmed valve implantation in both eyes and pars plana vitrectomy.

This particularly challenging case highlights the complex challenges in managing uveitis of unknown etiology, especially when complicated by secondary glaucoma. In young patients, progressive structural changes due to inflammation can rapidly lead to permanent vision loss. A combination of surgical procedures resulted in favorable anatomical and functional outcomes; however, long-term follow-ups remain essential to monitor for recurrent inflammation, intraocular pressure fluctuations, and other potential complications.

This case highlights the challenges and the need for a multidisciplinary approach in chronic, treatment-resistant uveitis with secondary complications.