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Incidence, characteristics, and predictive factors for medication errors in paediatric anaesthesia: a prospective
C Gariel1, B Cogniat1, F-P Desgranges1
1Department of Anaesthesia and Intensive Care, Femme Mère Enfant Hospital, Hospices Civils de Lyon, Bron, France.
Insights
Medication errors occurred in 2.6% of paediatric anaesthetics, with incorrect dosing being most common. Longer procedures (>120 min) were linked to increased risk of these critical medication errors.
Area of Science:
- Anesthesiology
- Pediatric Medicine
- Patient Safety
Background:
- Medication errors are frequent in hospitalized patients.
- Pediatric patients face higher risks due to complex dosing and drug preparation.
- This study investigated medication errors in pediatric anesthesia.
Purpose of the Study:
- Determine the incidence of medication errors in pediatric anesthesia.
- Identify characteristics of these errors.
- Find potential predictive factors for medication errors.
Main Methods:
- Prospective incident monitoring study.
- Conducted in a pediatric surgical center (Nov 2015 - Jan 2016).
- Included children (<18 yr) undergoing general anesthesia; anonymous incident forms completed by anesthesiologists.
Main Results:
- 37 medication errors (2.6%) reported in 1400 incident forms.
- Opioids and antibiotics were most common drugs involved.
- Incorrect dose (67.5%) was the primary error type; longer procedures (>120 min) were significantly associated with errors (aOR 4).
Conclusions:
- Medication errors are a significant concern in pediatric anesthesia.
- Understanding error mechanisms is crucial for developing preventive strategies.
- Further studies are needed to assess the effectiveness of preventive measures.
Background:
Medication errors are not uncommon in hospitalized patients. Paediatric patients may have increased risk for medication errors related to complexity of weight-based dosing calculations or problems with drug preparation and dilution. This study aimed to determine the incidence of medication errors in paediatric anaesthesia in a university paediatric hospital, and to identify their characteristics and potential predictive factors.
Methods:
This prospective incident monitoring study was conducted between November 2015 and January 2016 in an exclusively paediatric surgical centre. Children <18 yr undergoing general anaesthesia were consecutively included. For each procedure, an incident form was completed by the attending anaesthetist on an anonymous and voluntary basis.
Results:
Incident forms were completed in 1400 (73%) of the 1925 general anaesthetics performed during the study period with 37 reporting at least one medication error (2.6%). Drugs most commonly involved in medication errors were opioids and antibiotics. Incorrect dose was the most frequently reported type of error (n=27, 67.5%), with dilution error involved in 7/27 (26%) cases of incorrect dose. Duration of procedure >120 min was the only factor independently associated with medication error [adjusted odds ratio: 4 (95% confidence interval: 2-8); P=0.0001].
Conclusions:
Medication errors are not uncommon in paediatric anaesthesia. Identification of the mechanisms related to medication errors might allow preventive measures that can be assessed in further studies.
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