Related Experiment Video
Updated: Feb 14, 2026

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
Published on: August 23, 2019
Microbiota in fermented feed and swine gut.
Cheng Wang1, Changyou Shi1, Yu Zhang1
1National Engineering Laboratory of Biological Feed Safety and Pollution Prevention and Control, Key Laboratory of Animal Nutrition and Feed, Ministry of Agriculture, Key Laboratory of Animal Nutrition and Feed Science of Zhejiang Province, Institute of Feed Science, Zhejiang University, 866 Yuhang Tang Road, Hangzhou, 310058, Zhejiang, People's Republic of China.
Fermented feed (FF) positively impacts swine gut microbiota, offering a promising alternative to antibiotic growth promoters (AGP). This nutritional strategy enhances pig health and productivity by modulating gut bacteria.
Area of Science:
- Animal Science
- Microbiology
- Nutritional Science
Background:
- Antibiotic growth promoters (AGP) are widely used in swine production but their use necessitates alternatives due to growing concerns.
- Understanding the gut microbiota's role is crucial for developing effective AGP alternatives.
- Fermented feed (FF) presents a novel nutritional strategy with potential benefits for swine gut health.
Purpose of the Study:
- To review the impact of fermented feed (FF) on swine gut microbiota.
- To explore FF as a viable alternative to antibiotic growth promoters (AGP).
- To discuss the mechanisms by which FF influences gut microbial composition and function.
Main Methods:
- Literature review focusing on studies investigating fermented feed and swine gut microbiota.
- Analysis of existing research on the effects of FF on microbial shifts in different gastrointestinal tract (GIT) regions.
- Discussion of the potential prebiotic and probiotic effects of FF components.
Main Results:
- Fermented feed (FF) supplementation can positively modulate the swine gut microbiota.
- FF may lead to a shift in microbial balance favoring beneficial bacteria.
- The effects of FF are observed across various regions of the gastrointestinal tract (GIT).
Conclusions:
- Fermented feed (FF) shows significant potential as a natural alternative to AGP in swine diets.
- FF's positive influence on gut microbiota can contribute to improved pig productivity.
- Further research is needed to optimize FF fermentation and evaluation methods for consistent benefits.
Related Concept Videos
Fermentation
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
Microbial Fermentation
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Physiology of Enteric Nervous System and Gut Health
Ribosomes
Ribosome Structure and Assembly
Ribosomes are composed of ribosomal RNA (rRNA) and proteins. In eukaryotes, rRNA is transcribed from genes in the nucleolus—a part of the nucleus that specializes in ribosome...

