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Related Concept Videos

The Electromagnetic Spectrum02:37

The Electromagnetic Spectrum

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The electromagnetic spectrum consists of all the types of electromagnetic radiation arranged according to their frequency and wavelength. Each of the various colors of visible light has specific frequencies and wavelengths associated with them, and you can see that visible light makes up only a small portion of the electromagnetic spectrum. Because the technologies developed to work in various parts of the electromagnetic spectrum are different, for reasons of convenience and historical...
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The Electromagnetic Spectrum01:24

The Electromagnetic Spectrum

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Electromagnetic waves are categorized according to their wavelengths and frequencies, giving the electromagnetic spectrum. These waves are classified as radio, infrared, ultraviolet, etc. Radio waves refer to electromagnetic radiation with wavelengths ranging from millimeters to kilometers. Radio waves are commonly used for audio communications (i.e., radios) and typically result from an alternating current in the wires of a broadcast antenna. They cover a broad wavelength range and are used...
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IR Spectrum01:19

IR Spectrum

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When infrared (IR) radiation passes through a molecule, the bonds stretch or bend by absorbing the radiation. This absorption creates the molecule's absorption spectrum, which is the plot of its percentage transmittance versus wavenumber.
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0%...
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Light as Energy01:35

Light as Energy

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The energy required to carry out photosynthesis is light— typically electromagnetic radiation from the sun. The range of all possible wavelengths is known as the electromagnetic spectrum.
Photons
A photon is a discrete electromagnetic particle or bundle of energy. Photons are characterized by their frequency, wavelength, and amplitude, similar to the properties of a wave. Waves with higher frequencies transmit more energy and have shorter wavelengths than longer wavelengths that transmit...
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Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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Mass Spectrum01:23

Mass Spectrum

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A mass spectrum is the graphical representation of the relative abundance of the charged fragments in an analyte plotted against their mass-to-charge ratio (m/z). The plot's x-axis represents the ratio of the mass of the charged fragment to the number of charges it carries. The y axis of the plot represents the relative abundance of each charged species. The relative abundance is calculated from the signal intensity of each charged species recorded at the detector. The most intense signal (the...
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Light as a Broad-Spectrum Antimicrobial.

Peter J Gwynne1, Maurice P Gallagher1

  • 1School of Biology, University of Edinburgh, Edinburgh, United Kingdom.

Frontiers in Microbiology
|February 20, 2018
PubMed
Summary
This summary is machine-generated.

New antimicrobial strategies are needed due to rising antimicrobial resistance. Narrow-wavelength light shows promise for pathogen elimination, but further research is required to optimize its use.

Keywords:
antimicrobialsblue lightinfectioninfraredphotosensitizersphototherapyresistanceultraviolet

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Area of Science:

  • Microbiology
  • Photomedicine
  • Biophysics

Background:

  • Antimicrobial resistance (AMR) poses a significant global health threat, necessitating novel therapeutic strategies.
  • Conventional antimicrobial therapies are becoming less effective against resistant pathogens.
  • Narrow-wavelength light presents a potential alternative or complementary approach to combat microbial infections.

Purpose of the Study:

  • To explore the potential of narrow-wavelength light as an antimicrobial agent.
  • To highlight the need for further research into light-based antimicrobial therapies.
  • To discuss key areas requiring investigation for effective implementation of light therapy.

Main Methods:

  • Review of existing research on light-based antimicrobial approaches.
  • Discussion of the electromagnetic spectrum's potential beyond blue light.
  • Analysis of factors influencing light's antimicrobial efficacy and safety.

Main Results:

  • Narrow-wavelength light has demonstrated efficacy in eliminating various common pathogens.
  • Blue light has shown progress, but other spectral regions remain largely unexplored.
  • Optimal energy dose, effects on eukaryotic tissues, and the role of oxygen are critical research areas.

Conclusions:

  • Further research is essential to fully realize the potential of light-based antimicrobial therapies.
  • Investigating energy dose, host tissue interactions, and oxygen's role will be crucial for clinical translation.
  • Optimizing light therapy requires a comprehensive understanding of its mechanisms and parameters.