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Updated: Feb 14, 2026

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Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
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Post-Vacuum-Assisted Stereotactic Core Biopsy Clip Displacement: A Comparison Between Commercially Available Clips
Peggy Yen1, Sandra Dumas2, Arianne Albert3
1Department of Diagnostic Radiology, Nanaimo Regional General Hospital, Nanaimo, British Columbia, Canada.
Summary
Commercial biopsy clips reduce displacement after stereotactic vacuum-assisted core biopsy compared to surgical clips. This improves imaging surveillance and surgical planning by minimizing clip migration.
Area of Science:
- Radiology
- Surgical Oncology
- Medical Devices
Background:
- Localization clip placement after percutaneous biopsy is standard practice.
- Clip displacement poses challenges for imaging, surgical planning, and interdisciplinary communication.
- The "accordion effect" is a commonly cited cause of clip displacement.
Purpose of the Study:
- To compare the performance of a low-cost surgical clip system against four commercially available clips.
- To evaluate clip displacement following stereotactic vacuum-assisted core biopsy.
Main Methods:
- Retrospective review of 2112 patients undergoing stereotactic vacuum-assisted core biopsy with clip placement (January 2013 - June 2016).
- Primary outcome: displacement >10 mm.
- Secondary outcome: magnitude of displacement for displaced clips.
Main Results:
- Significant differences in displacement among clip types (P < .0001).
- Pediatric surgical clips showed higher displacement rates (38%) compared to SecureMark (28%) and SenoMark (27%).
- Surgical clips exhibited a ~25% greater average displacement distance.
Conclusions:
- Commercial clips generally outperformed surgical clips in minimizing displacement after stereotactic vacuum-assisted core biopsy.
- The anchoring effect of the outer component in commercial clips likely reduces displacement.
- Findings are potentially applicable to tomosynthesis-guided biopsies.
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