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Layer Microdissection of Tricuspid Valve Leaflets for Biaxial Mechanical Characterization and Microstructural Quantification
Published on: February 10, 2022
Pattern and Extent of Tricuspid Valve Involvement in Chronic Rheumatic Heart Disease
M B Rashid1, T Parvin, C M Ahmed
1Dr Mohammad Bazlur Rashid, Medical Officer, Singair Upozilla Health Complex, Bangladesh.
Insights
Tricuspid valve disease is a common complication of Rheumatic Heart Disease (RHD) in Bangladesh, often presenting with thickened leaflets, stenosis, or regurgitation. Early recognition and treatment of tricuspid valve involvement can improve patient outcomes.
Area of Science:
- Cardiology
- Echocardiography
- Rheumatic Heart Disease
Background:
- Rheumatic Heart Disease (RHD) is a major cause of morbidity and mortality in Bangladesh.
- While mitral and aortic valves are commonly affected, tricuspid valve disease in RHD is often overlooked.
- Tricuspid valve disease can significantly impact long-term functional outcomes in RHD patients.
Purpose of the Study:
- To investigate the pattern and extent of tricuspid valve involvement in patients with Rheumatic Heart Disease.
- To provide recent data on tricuspid valve disease prevalence in RHD.
Main Methods:
- An observational analytical study conducted at Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
- Data collected from 173 Chronic Rheumatic Heart Disease patients undergoing Echocardiography (2D, M-mode, Doppler).
- Focus on identifying tricuspid valve abnormalities.
Main Results:
- Tricuspid valve involvement was identified in 36 out of 173 RHD patients (20.8%).
- Common findings included tricuspid regurgitation (36 patients) and tricuspid stenosis (15 patients).
- All affected patients exhibited thickened tricuspid valve leaflets, with varying degrees of doming, restricted motion, and calcification.
Conclusions:
- Organic tricuspid valve involvement is a frequent occurrence in Rheumatic Heart Disease patients in Bangladesh.
- The findings highlight the need for greater attention to tricuspid valve pathology in RHD management.
- Further research into the specific patterns and clinical implications of tricuspid valve disease in RHD is warranted.
Abstract:
Rheumatic heart disease causes a significant number of morbidity and mortality in Bangladesh. Although the mitral and the aortic valve are the two most involved valves in rheumatic heart disease, the tricuspid valve disease is not uncommon secondary to, or in association with, mitral or aortic valve disease, but receives less attention as compared to the primary left-sided valve disease. Appropriate treatment of the tricuspid valve disease may improve long-term functional outcome. But the pattern and extent of the tricuspid valve involvement was not studied recently. This study was carried out to observe the pattern and extent of tricuspid valve involvement in Rheumatic Heart Disease patients. This observational analytical study was undertaken in the department of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from December 2010 to September 2011. Considering all ethical issues, data were collected from 173 subjects who underwent Echocardiography for their Chronic Rheumatic heart disease. Pattern of tricuspid valve involvement was observed by using Transthoracic Echocardiography by 2D, M mode and Doppler assessment. One hundred seventy three (173) patients with Rheumatic Heart disease was studied, out of these, 36 patients had evidence of tricuspid valve involvement based on echocardiographic findings. Fifteen (15) patients had Tricuspid stenosis and 36 patients had Tricuspid Regurgitation in the patients with TV involvement. All the patients with TV involvement had thickened leaflets. Doming, restriction of motion and calcification were present in different proportions. From this study, it can be concluded that organic tricuspid valve involvement in RHD is not uncommon in our country.
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The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Anatomy of the Heart

