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Medication adherence in pediatric asthma: A systematic review of the literature

Wendy N Gray1, Mallory Netz2, Andrew McConville2

  • 1Department of Psychology, Auburn University, Auburn University, AL.

Pediatric Pulmonology
|February 21, 2018
PubMed

Insights

Adherence to inhaled corticosteroids (ICS) in pediatric asthma is influenced by individual, family, and healthcare factors. More research is needed to understand how these multiple domains interact to affect medication adherence in youth.

Area of Science:

  • Pediatric pulmonology
  • Behavioral science
  • Health services research

Background:

  • Pediatric asthma management relies heavily on adherence to inhaled corticosteroids (ICS).
  • Understanding factors influencing ICS adherence in children and adolescents is crucial for effective disease control.
  • Existing research often examines correlates within isolated domains, limiting a holistic view.

Purpose of the Study:

  • To systematically review correlates of inhaled corticosteroids (ICS) adherence in pediatric asthma.
  • To examine adherence factors across individual, family, community, and healthcare system domains.
  • To identify gaps in current research regarding pediatric asthma medication adherence.

Main Methods:

  • Systematic review of articles published between 1997 and 2016 in PsychINFO, Medline, and CINAHL.
  • Inclusion criteria: US-published studies, pediatric populations (0-25 years), original data on ICS adherence.
  • Correlates categorized using the Pediatric Self-Management Model; study quality was assessed.

Main Results:

  • Seventy-nine articles were reviewed, with family-level correlates (e.g., socioeconomic status, knowledge) most frequently reported.
  • Individual-level correlates, particularly age, were also significant.
  • Healthcare system factors like enhanced care and communication were associated with adherence; community factors were less studied.

Conclusions:

  • Adherence to ICS in pediatric asthma is influenced by multiple domains of the Pediatric Self-Management Model.
  • Current research predominantly focuses on single-domain correlates, necessitating a more integrated approach.
  • Future studies should investigate cross-domain interactions to better understand determinants of pediatric asthma medication adherence.
Abstract

Keywords:
adherencechild/adolescentcommunityfamilyhealth care system

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