Related Experiment Video

Updated: Aug 5, 2026

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles
09:04

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles

Published on: May 2, 2014

11.8K

[Juvenile idiopathic arthritis]

E J H Schatorjé, A van Royen-Kerkhof

    Nederlands Tijdschrift Voor Tandheelkunde
    |February 21, 2018
    PubMed

    Insights

    Juvenile idiopathic arthritis (JIA) can cause dental issues, including temporomandibular joint (TMJ) arthritis. Early detection by dentists is crucial for managing this common childhood inflammatory joint disease.

    Area of Science:

    • Pediatric Rheumatology
    • Pediatric Dentistry
    • Oral Medicine

    Background:

    • Juvenile idiopathic arthritis (JIA) is a leading cause of chronic childhood joint inflammation.
    • JIA presents with 7 subtypes based on early symptoms, influencing treatment.
    • Dental complications are common in JIA patients.

    Purpose of the Study:

    • To highlight the dental complications associated with JIA.
    • To emphasize the diagnostic challenges of temporomandibular joint (TMJ) arthritis in JIA.
    • To explore the potential role of dentists in identifying TMJ arthritis in children with JIA.

    Main Methods:

    • Review of existing literature on JIA and its oral manifestations.
    • Analysis of common dental problems in JIA patients, including caries, stomatitis, and candidiasis.
    • Discussion of the clinical presentation and diagnostic difficulties of TMJ arthritis in JIA.

    Main Results:

    • JIA patients are at increased risk for dental caries.
    • Methotrexate use can lead to stomatitis, and immunosuppressants may cause oral candidiasis.
    • Temporomandibular joint (TMJ) arthritis is a challenging complication to detect in routine JIA care.

    Conclusions:

    • Dental health monitoring is essential for children with JIA.
    • Dentists are well-positioned to identify early signs of TMJ arthritis in JIA patients.
    • Interdisciplinary collaboration between rheumatologists and dentists can improve JIA management.

    More Related Videos

    An Adoptive Transfer Model of Rheumatoid Arthritis in Mice07:37

    An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

    Published on: June 6, 2025

    1.2K
    Refined Murine Model of Idiopathic Pulmonary Fibrosis07:51

    Refined Murine Model of Idiopathic Pulmonary Fibrosis

    Published on: June 17, 2025

    1.1K

    Related Concept Videos

    Autoimmune Disorders01:29

    Autoimmune Disorders

    Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
    Concept and Mechanism of Autoimmune Diseases
    The immune system...
    Inflammatory Bowel Disease II: Crohn's Disease01:30

    Inflammatory Bowel Disease II: Crohn's Disease

    Introduction
    Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
    Crohn's disease
    Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
    Rheumatic Heart Disease I: Introduction01:23

    Rheumatic Heart Disease I: Introduction

    Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
    Chronic Inflammation: Introduction01:12

    Chronic Inflammation: Introduction

    Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
    Inflammatory Bowel Disease III: Crohn's Disease01:25

    Inflammatory Bowel Disease III: Crohn's Disease

    Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
    Inflammatory Bowel Disease IV: Clinical Manifestations01:20

    Inflammatory Bowel Disease IV: Clinical Manifestations

    Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...