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Generation of Alginate Microspheres for Biomedical Applications
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Black Phosphorus and its Biomedical Applications.

Jane Ru Choi1, Kar Wey Yong2, Jean Yu Choi3

  • 1Food, Nutrition and Health Programs, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.

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|February 22, 2018
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Summary

Black phosphorus (BP), a novel 2D material, shows promise for biomedical uses due to its unique properties. This review explores BP

Keywords:
biosensingblack phosphorusdrug deliveryphotoacoustic imagingphotothermal and photodynamic therapies.

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Area of Science:

  • Materials Science and Engineering
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Black phosphorus (BP), also known as phosphorene, has emerged as a significant 2D material since its exfoliation in 2014.
  • BP possesses unique optical, mechanical, electrical, and electron-transfer properties, positioning it as a potential alternative to graphene in various applications.
  • Its distinct characteristics make it a compelling candidate for advanced biomedical applications, driving research interest.

Purpose of the Study:

  • To review the unique properties of black phosphorus (BP) that make it suitable for biomedical applications.
  • To compare BP with other 2D materials like graphene, MoS2, WSe2, and h-BN for biomedical potential.
  • To discuss synthesis methods and recent advancements in BP's use for biosensing, drug delivery, photoacoustic imaging, and cancer therapies.

Main Methods:

  • Comprehensive literature review of black phosphorus synthesis and properties.
  • Comparative analysis of BP against other 2D materials for biomedical relevance.
  • Survey of current research on BP applications in diagnostics and therapeutics.

Main Results:

  • Black phosphorus exhibits superior optical and electrical properties compared to many other 2D materials.
  • BP has demonstrated efficacy in preliminary studies for biosensing, drug delivery, photoacoustic imaging, and cancer treatments (photothermal and photodynamic therapies).
  • Various synthesis methods are available, though challenges remain in large-scale production and stability.

Conclusions:

  • Black phosphorus holds significant potential for diverse biomedical applications due to its exceptional properties.
  • Further research is needed to overcome existing challenges in synthesis, stability, and clinical translation.
  • BP represents a promising frontier in nanomedicine and advanced material-based healthcare solutions.