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Updated: Feb 14, 2026

Preparation of Keratin Hydrolysate from Chicken Feathers and Its Application in Cosmetics
Published on: November 27, 2017
New bioprinted skin, cosmetic in vitro model
Sebastien Cadau1, Delphine Rival1, Valerie Andre-Frei1
1BASF Beauty Care Solutions, Lyon, France (S.C., D.R., V.A.), Poietis, Pessac, France (D.F., B.B., F.G.), and BASF Corporation, Tarrytown, NY 10591 (M.C.).
Abstract:
We developed a new evolution of three-dimensional skin equivalent due to the optimization of four-dimensional laser-assisted bioprinting and skin equivalent culture protocols. This allowed us to produce fully bioprinted skin equivalents that are closed to current skin equivalents and suitable to test cosmetic ingredients. Particularly, we performed preliminary evaluation of maturogens to improve the dermis maturation before the epidermal seeding and we designed a specific "micropattern" to reproduce the nonlinear aspect of the dermal-epidermal junction. Finally an active ingredient was applied during the production of the bioprinted skin equivalent.
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