Related Experiment Video
Updated: Feb 14, 2026

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
Cobalt-Catalyzed, N-H Imine-Directed Hydroarylation of Styrenes
Wengang Xu1, Naohiko Yoshikai1
1Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University , Singapore 637371, Singapore.
Abstract:
A cobalt-catalyzed, N-H imine-directed hydroarylation reaction of styrenes is reported. A variety of diaryl and aryl alkyl N-H imines participated in the reaction to afford the corresponding branched adducts in good yield and regioselectivity. Interestingly, unsymmetrical diaryl imines with modest electronic biases reacted regioselectively at one of the aryl rings. Furthermore, the branched selectivity was reversed for substrates bearing a secondary directing group or a bulky pivaloyl N-H imine.
More Related Videos
06:31Preparation of SNS CobaltII Pincer Model Complexes of Liver Alcohol Dehydrogenase
Published on: March 19, 2020
10:31Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores
Published on: December 6, 2015
Related Concept Videos
Aldehydes and Ketones with Amines: Imine Formation Mechanism
Imines are formed under mildly acidic conditions. A pH of 4.5 is ideal for the reaction.
If the pH is low or the solution is too acidic, the reaction slows down in the...
Acid-Catalyzed Ring-Opening of Epoxides
Base-Catalyzed Ring-Opening of Epoxides
Aldehydes and Ketones with Amines: Imine and Enamine Formation Overview
Base-Catalyzed Aldol Addition Reaction
Acid-Catalyzed Dehydration of Alcohols to Alkenes