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Annular elastolytic giant cell granuloma: a "visible" diagnosis
Inês Raposo1, Fernando Mota, Inês Lobo
1Department of Dermatology, Centro Hospitalar do Porto, Portugal. inesraposovs@gmail.com.
Dermatology Online Journal
|February 23, 2018
Summary
Annular elastolytic giant cell granuloma (AEGCG) is a rare skin condition. Hydroxychloroquine effectively treated a patient with AEGCG, showing excellent clinical response.
Area of Science:
- Dermatology
- Granulomatous skin diseases
Background:
- Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease.
- Its etiology remains undetermined.
- Characterized by annular plaques with raised erythematous borders, typically on sun-exposed skin.
Observation:
- A clinical case of AEGCG is presented.
- The patient exhibited typical clinical and histological features.
- Histopathology revealed dermal infiltration by multinucleated giant cells, elastin degeneration, and elastophagocytosis.
Findings:
- The patient showed an excellent response to hydroxychloroquine treatment.
- Hydroxychloroquine is a potential therapeutic option for AEGCG.
Implications:
- This case highlights hydroxychloroquine as an effective treatment for AEGCG.
- Further research may explore hydroxychloroquine's role in managing this rare granulomatous skin condition.