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Updated: Feb 14, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
A toxic epidermal necrolysis-like presentation of linear IgA bullous dermatosis treated with dapsone
Julie K Nguyen, Misha V Koshelev, Bartley J Gill
1Department of Dermatology, Baylor College of Medicine, Houston, Texas. hdao@bcm.edu.
Abstract:
Linear IgA bullous dermatosis is a rare autoimmune vesiculobullous disease characterized by linear deposition of IgA along the basement membrane zone. It is classically idiopathic, but may also arise secondary to drug exposure. A heterogeneous spectrum of clinical features has been described, including a rare, morbid variant mimicking toxic epidermal necrolysis. Herein, we present a case of vancomycin-induced linear IgA bullous dermatosis that manifested clinically as toxic epidermal necrolysis and resolved with dapsone therapy.
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