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HYDRATION FOLDS IN RHEGMATOGENOUS RETINAL DETACHMENT
Lauren A Dalvin1, Richard F Spaide2, Lawrence A Yannuzzi2
1Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
Retinal Cases & Brief Reports
|February 23, 2018
Summary
Retinal hydration folds, outer retinal abnormalities, were observed in two cases of retinal detachment. These folds may result from glycosaminoglycan hydration in the interphotoreceptor matrix.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Pathophysiology
Background:
- Retinal detachment is a serious condition affecting vision.
- Outer retinal abnormalities can complicate diagnosis and understanding of retinal detachment.
Observation:
- Two patients presented with retinal detachment and distinct outer retinal abnormalities termed hydration folds.
- One patient had a macular hole-related detachment, the other a rhegmatogenous detachment mimicking exudative detachment.
Findings:
- Near-infrared reflectance imaging showed hydration folds resembling eddy currents.
- Optical coherence tomography revealed curvilinear outer retinal plications with thickened, elongated photoreceptor outer segments and lateral expansion.
Implications:
- Hydration folds have characteristic imaging features on near-infrared imaging and OCT in rhegmatogenous retinal detachment.
- The exact cause of these folds is unknown, but hydration of interphotoreceptor matrix glycosaminoglycans is suspected.
- Further research is needed to elucidate the pathophysiology of hydration folds in retinal detachment.
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