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Updated: Jan 20, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Diagnostic and therapeutic spinal interventions: Epidural injections
J D Bartleson1, Timothy P Maus1
1Departments of Neurology (JDB) and Radiology (TPM), Mayo Clinic, Rochester, MN.
Epidural injections, including corticosteroids, can diagnose and treat spinal radicular pain, offering substantial benefits for many patients. Selective nerve blocks help identify pain sources, with risks generally being rare and infrequent.
Area of Science:
- Pain Medicine
- Neurology
- Interventional Radiology
Background:
- Epidural injections are common for diagnosing and treating radicular pain.
- Transforaminal approach in the lumbar spine has strong evidence.
- Selective nerve blocks can identify specific pain-causing nerves.
Purpose of the Study:
- To review the diagnostic and therapeutic applications of epidural injections for radicular pain.
- To highlight the evidence supporting the transforaminal approach.
- To discuss patient selection and potential risks.
Main Methods:
- Review of existing evidence on epidural injections.
- Analysis of diagnostic utility of selective nerve blocks.
- Assessment of risks associated with epidural steroid injections.
Main Results:
- Many patients experience significant benefit from a single therapeutic epidural injection.
- Transforaminal lumbar epidural injections show the best evidence.
- Short-term serious risks are rare; long-term risks are infrequent.
Conclusions:
- Epidural injections are a valuable tool for managing radicular pain.
- Patient selection is key, particularly for those failing conservative therapy.
- Careful consideration of risks versus benefits is necessary for optimal patient outcomes.
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