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Updated: Feb 14, 2026

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
Published on: January 3, 2025
SDG721 and SDG705 are required for rice growth
Pengfei Jiang1,2, Shiliang Wang1,2, Aziz Ul Ikram2
1National Engineering Laboratory of Crop Stress Resistance/ Key Laboratory of Crop Biology of Anhui Province, School of Life Sciences, Anhui Agricultural University, Hefei 230036, China.
SDG721 and SDG705 proteins regulate rice development by modulating H3K4 methylation. Loss of these genes causes gibberellin deficiency, impacting plant growth and development.
Area of Science:
- Plant Biology
- Epigenetics
- Molecular Biology
Background:
- Histone H3 lysine 4 trimethylation (H3K4me3) is a key epigenetic mark regulating gene expression crucial for development.
- TRITHORAX-like proteins are known regulators of H3K4 methylation in various organisms.
- Understanding epigenetic regulation in rice is vital for improving crop yields and stress resilience.
Discussion:
- SDG721 and SDG705 encode TRITHORAX-like proteins involved in rice development.
- These proteins modulate H3K4 methylation levels, influencing gene expression.
- The study links SDG721/SDG705 to gibberellin (GA) biosynthesis and signaling pathways.
Key Insights:
- Loss of SDG721 and SDG705 function leads to GA-deficient phenotypes in rice, including semi-dwarfism and reduced panicle branching.
- H3K4me3 levels of GA biosynthesis and signaling genes are downregulated in sdg721 sdg705 mutant plants.
- SDG721 and SDG705 are essential for normal rice development through epigenetic control of GA homeostasis.
Outlook:
- Further research can explore the precise mechanisms by which SDG721/SDG705 regulate H3K4 methylation at specific target genes.
- Investigating the interaction of SDG721/SDG705 with other epigenetic modifiers could reveal complex regulatory networks.
- Harnessing the function of SDG721 and SDG705 may offer novel strategies for breeding improved rice varieties with enhanced growth characteristics.
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