Related Experiment Video
Updated: Feb 14, 2026

Labeling F-actin Barbed Ends with Rhodamine-actin in Permeabilized Neuronal Growth Cones
Published on: March 17, 2011
Effectiveness, Longevity, and Complications of Facelift by Barbed Suture Insertion
Dario Bertossi1, Giovanni Botti2, Alessandro Gualdi3
1Section of Oral and Maxillofacial Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.
Facelift with barbed polydioxanone (PDO) threads offers temporary improvement in facial ptosis but has a high complication rate. The procedure
Area of Science:
- Plastic Surgery
- Dermatology
- Aesthetic Medicine
Background:
- Minimally invasive facelift techniques using barbed sutures are increasingly popular for addressing facial tissue ptosis.
- Barbed polydioxanone (PDO) threads offer a less invasive approach compared to traditional facelift surgeries.
Purpose of the Study:
- To evaluate the effectiveness, longevity, and complications of facelift procedures using barbed PDO threads.
- To assess the long-term outcomes and patient sequelae associated with this minimally invasive technique.
Main Methods:
- A retrospective analysis of 160 consecutive patients who underwent facelift with barbed threads.
- Standardized placement of PDO threads (23 or 21 gauge) for malar augmentation, nasolabial groove correction, and mandibular line treatment.
Main Results:
- Immediate improvement in facial tissue ptosis was observed, lasting up to 1 month.
- Aesthetic results declined by 6 months and were absent by 1 year post-procedure.
- The overall complication rate was 34%, including suture displacement, erythema, infection, skin dimpling, and temporary facial stiffness.
Conclusions:
- Barbed thread facelifts provide transient aesthetic benefits for facial ptosis.
- The significant complication rate suggests limiting this procedure to patients unsuitable for more invasive facial surgery.
Related Concept Videos
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Hemodialysis II: Procedure and Complications
Pneumonia III: Complications and Assessment
Diabetes: Symptoms, Diagnosis, and Complications
Asthma-III: Symptoms and Complications
Classification of Asthma
Buffer Effectiveness
The buffer capacity is the amount of acid or base that can be added to a given volume...

