Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Purposive Learning01:22

Purposive Learning

519
E. C. Tolman emphasized the purposiveness of behavior — the idea that much of our behavior is goal-directed. For instance, employees who aim for a promotion work diligently to meet their targets. Tolman argued that when classical conditioning and operant conditioning occur, the organism acquires certain expectations. In classical conditioning, a child might fear a dog because they expect it to bite. In operant conditioning, a person might consistently work overtime because they expect a...
519
Purpose of Health Records I01:11

Purpose of Health Records I

1.8K
The vital purpose of health records is to provide a complete and accurate account of a patient's medical history, including communication, diagnostic and therapeutic orders, care planning, research, and quality review.
Here's a breakdown of how health records serve these purposes:
1.8K
Purpose of Health Records II01:19

Purpose of Health Records II

1.5K
Health records serve various essential purposes in the healthcare system. Here are some key purposes:
1.5K
Horizontal Gene Transfer01:27

Horizontal Gene Transfer

2.3K
Horizontal gene transfer (HGT) is a process where genetic material moves between organisms within the same generation, unlike vertical gene transfer, which occurs from parent to offspring. HGT plays a crucial role in microbial evolution, adaptation, and survival, particularly in shared environments like the human gut.Mobile genetic elements such as plasmids, prophages, integrons, insertion sequences, and transposons facilitate this process. HGT occurs through three primary mechanisms:...
2.3K
Introduction to Horizontal Curves01:19

Introduction to Horizontal Curves

757
Horizontal curves are essential in highway and railroad design, ensuring smooth and safe transitions between straight path segments, or tangents. These curves allow vehicles to maintain speed without abrupt changes, minimizing accidents and improving travel efficiency.A horizontal curve is typically defined by its geometric relationship to two tangents that meet at an intersection point (P.I.), where a simple curve is introduced to connect them. The back tangent refers to the initial tangent...
757
Horizontal Curve: Problem Solving01:03

Horizontal Curve: Problem Solving

421
A horizontal curve is characterized by its radius, intersection angle, and stationing of key points. In this case, the radius is 400 meters, and the angle of intersection is 30 degrees, with the station of the point of curvature (P.C.) at 0 + 150 meters. The goal is to determine the station values at the point of intersection (P.I.), point of tangency (P.T.), and midpoint of the curve, as well as the length of the long chord.The process begins with calculating the tangent distance (T) and the...
421

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RENEB Inter-Laboratory Comparison 2021: Inter-Assay Comparison of Eight Dosimetry Assays.

Radiation research·2023
Same author

RENEB Inter-Laboratory Comparison 2021: The Cytokinesis-Block Micronucleus Assay.

Radiation research·2023
Same author

Traceable dosimetry for MeV ion beams.

Journal of instrumentation : an IOP and SISSA journal·2022
Same author

Proton Irradiation Platforms for Preclinical Studies of High-Dose-Rate (FLASH) Effects at RARAF.

Radiation research·2020
Same author

DEMONSTRATION OF THE POTENTIAL AND DIFFICULTIES OF COMBINED TL AND OSL MEASUREMENTS OF TLD-600 AND TLD-700 FOR THE DETERMINATION OF THE DOSE COMPONENTS IN COMPLEX NEUTRON-GAMMA RADIATION FIELDS.

Radiation protection dosimetry·2020
Same author

LET dependent response of GafChromic films investigated with MeV ion beams.

Physics in medicine and biology·2018
Same journal

Design and realization of a sputter deposition system for the <i>in situ</i> and <i>in operando</i> use in polarized neutron reflectometry experiments: Novel capabilities.

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment·2026
Same journal

Monte Carlo Modeling of An Experimental Benchtop L-shell X-ray Fluorescence Imaging/CT System Adopting Two Silicone Drift Detectors.

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment·2025
Same journal

Autonomous screening of complex phase spaces using Bayesian optimization for SAXS measurements.

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment·2025
Same journal

Integration of an electron beam ion trap source into an electrostatic accelerator for pre-clinical cancer research.

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment·2025
Same journal

Characterization of external optical crosstalk reduction for SiPM-based scintillation detectors with an optical bandpass filter.

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment·2025
Same journal

Cold neutron radiation dose effects on a <sup>6</sup>LiF:ZnS(Ag) neutron detector with wavelength shifting fibers and SiPM photodetector.

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment·2024
See all related articles

Related Experiment Video

Updated: Feb 14, 2026

Manufacture of a Multi-Purpose Low-Cost Animal Bench-Model for Teaching Tracheostomy
10:06

Manufacture of a Multi-Purpose Low-Cost Animal Bench-Model for Teaching Tracheostomy

Published on: May 18, 2019

6.0K

A Horizontal Multi-Purpose Microbeam System.

Y Xu1, G Randers-Pehrson2, S A Marino2

  • 1Physics Department, East Carolina University, Greenville, NC 27858, USA.

Nuclear Instruments & Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment
|February 27, 2018
PubMed
Summary
This summary is machine-generated.

A new microbeam system at Columbia University enables precise single cell irradiation and serves as a primary beam for advanced experiments. This system achieves micrometer-size beams for detailed research applications.

More Related Videos

Horizontal Hippocampal Slices of the Mouse Brain
08:59

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

20.9K
Horizontal Slice Preparation of the Retina
10:45

Horizontal Slice Preparation of the Retina

Published on: November 20, 2006

16.2K

Related Experiment Videos

Last Updated: Feb 14, 2026

Manufacture of a Multi-Purpose Low-Cost Animal Bench-Model for Teaching Tracheostomy
10:06

Manufacture of a Multi-Purpose Low-Cost Animal Bench-Model for Teaching Tracheostomy

Published on: May 18, 2019

6.0K
Horizontal Hippocampal Slices of the Mouse Brain
08:59

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

20.9K
Horizontal Slice Preparation of the Retina
10:45

Horizontal Slice Preparation of the Retina

Published on: November 20, 2006

16.2K

Area of Science:

  • Physics
  • Radiological Research
  • Accelerator Science

Background:

  • Developing precise microbeam systems is crucial for advanced cellular and material analysis.
  • Existing systems often lack the flexibility for diverse experimental needs.

Purpose of the Study:

  • To develop and optimize a horizontal multi-purpose microbeam system for single cell irradiation and other applications.
  • To achieve micrometer-size beams with high particle fluence.

Main Methods:

  • Utilized a single electrostatic quadruplet focusing lens.
  • Coupled the system with a 5.5 MV Singleton accelerator.
  • Employed ray tracing simulations for optimization.
  • Verified beam spot size through experimental measurements.

Main Results:

  • Successfully developed a horizontal multi-purpose microbeam system.
  • Achieved micrometer-size beams suitable for single cell irradiation.
  • Demonstrated utility as a primary beam for neutron microbeam and microPIXE experiments due to high particle fluence.

Conclusions:

  • The developed microbeam system offers a versatile platform for various research applications.
  • The system's optimization ensures high precision and particle fluence for demanding experiments.