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Updated: Feb 14, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Normal Variants and Pitfalls Encountered in PET Assessment of Gynecologic Malignancies
Jian Q Yu1, Mohan Doss2, R Katherine Alpaugh3
1Nuclear Medicine and PET Service, Department of Diagnostic Imaging, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
Abstract:
Combined PET/computed tomography is used for oncological indications. PET/computed tomography benefits from the metabolic information of PET and the anatomic localization of computed tomography. The integrated scanner provides data with accurate registration of anatomy and molecular information. Many physiologic conditions, normal variants, and benign lesions within the pelvis and the body can cause confusion and uncertainty. False-negative results owing to low 18F-fluorodeoxyglucose uptake from the tumor can produce diagnostic challenges and inaccurate conclusions. This article reviews normal variants and potential pitfalls encountered in PET assessment of gynecologic malignancies to provide useful information for the referring and reporting physicians.
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