Genomics
Human Genetics
Genetics of Speciation
Genome Size and the Evolution of New Genes
What is Genetic Engineering?
Cell Diversity
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Generation of Defined Genomic Modifications Using CRISPR-CAS9 in Human Pluripotent Stem Cells
Published on: September 25, 2019
Julia di Iulio1,2, Istvan Bartha1,3, Emily H M Wong1
1Human Longevity, Inc., San Diego, CA, USA.
A new map of human genome sequence constraint reveals that essential genes and regulatory elements are highly conserved. This map aids in interpreting noncoding genetic variants and prioritizing pathogenic mutations.
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