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Vapocoolant Anesthesia for Cosmetic Facial Rejuvenation Injections: A Randomized, Prospective, Split-Face Trial.

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Vapocoolant spray significantly reduces pain during cosmetic facial injections. This novel approach offers a virtually pain-free experience for patients undergoing neurotoxin or filler treatments, enhancing satisfaction.

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Area of Science:

  • Aesthetic Medicine
  • Dermatology
  • Plastic Surgery

Background:

  • Minimally invasive cosmetic procedures are prevalent, with patient demand for pain-free experiences.
  • Vapocoolant technology has demonstrated efficacy in reducing pain during other medical procedures.
  • Its application in facial rejuvenation via neurotoxin and filler injections is a novel area of investigation.

Purpose of the Study:

  • To evaluate the efficacy of vapocoolant spray in reducing pain associated with facial rejuvenation procedures.
  • To compare pain perception during neurotoxin and filler injections with and without vapocoolant application.

Main Methods:

  • A randomized, prospective, split-face study involving 30 subjects (15 filler, 15 neurotoxin).
  • Vapocoolant spray (95:5 1,1,1,3,3-pentafluoropropane/1,1,1,2-tetrafluoroethane) applied to one half of the face during injection.
  • Pain scores (1-10 scale) assessed by an independent examiner for both treated and control sides.

Main Results:

  • Vapocoolant spray resulted in a 59% decrease in perceived pain for neurotoxin injections.
  • A 64% decrease in perceived pain was observed for filler injections.
  • Both outcomes were statistically significant (P < .05).

Conclusions:

  • Vapocoolant spray is an effective method for reducing pain during cosmetic facial injections.
  • This technique enhances patient comfort during neurotoxin and filler procedures.
  • Offers a novel, evidence-based approach to improve patient experience in aesthetic treatments.