Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Standard Electrode Potentials03:02

Standard Electrode Potentials

50.5K
On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
50.5K
Density00:56

Density

20.0K
Density is an important characteristic of substances, crucial in determining whether an object sinks or floats in a fluid. Its SI unit is kg/m3, and its cgs unit is g/cm3. The density of an object helps in identifying its composition, and also reveals information about the phase of the matter and its substructure. The densities of liquids and solids are roughly comparable, consistent with the fact that their atoms are in close contact. However, gases have much lower densities than liquids and...
20.0K
Current Density01:21

Current Density

5.2K
The total amount of current flowing through one unit value of a cross-sectional area is referred to as current density. If the current flow is uniform, the amount of current flowing through a conductor is the same at all points along the conductor, even if the conductor area varies. The current density consists of the local magnitude and direction of the charge flow, which varies from point to point. Current density is measured in amperes per meter square, and direction is defined as the net...
5.2K
Electrodes: Overview01:17

Electrodes: Overview

2.8K
 Electrochemical measurements are conducted in an electrochemical cell composed of various components that control and measure the current and potential. One fundamental component is electrodes, conductive materials that enable electron transfer reactions at their surfaces.
There are two main types of electrodes in electrochemical cells. The first type, known as the working or indicator electrode, has a potential that is sensitive to the analyte's concentration and reacts to changes in...
2.8K
Neural Regulation01:37

Neural Regulation

43.5K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.5K
Strain-Energy Density01:20

Strain-Energy Density

943
Understanding the strain energy density in materials under axial load is crucial for evaluating their mechanical behavior and durability. When a rod is subjected to such a load, it elongates and stores energy, known as strain energy, as potential energy within the material. This energy is measured in terms of energy per unit volume.
In the elastic region of a material, the relationship between the stress and the strain is linear and follows Hooke's Law. The strain energy density in this region...
943

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Subspace communication in the hippocampal-retrosplenial axis.

Nature·2026
Same author

An integrated <i>i</i> <i>n vitro</i> platform and biophysical modeling approach for studying synaptic transmission in isolated neuronal pairs.

iScience·2026
Same author

Dentate gyrus interneurons modulate winner-take-all network dynamics in freely behaving mice.

Neuron·2026
Same author

Sharp wave-ripple clusters enhance hippocampal-neocortical engagement for memory consolidation.

bioRxiv : the preprint server for biology·2026
Same author

Usability and Acceptance of Non-Functional Wearable Prototypes for Maternal Health: A Parallel-Group Pilot Study.

Healthcare (Basel, Switzerland)·2026
Same author

Inkube: an all-in-one solution for neuron culturing, electrophysiology, and fluidic exchange.

Lab on a chip·2026
Same journal

Amorphous High-Entropy Oxides With High-Valent Metal and Oxygen-Vacancy Pairs for Thermally Stable Catalytic Oxidation.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

H<sub>2</sub>S Self-Supplied Micelles Reverse Tumor-Immune Effector Cells Energy Metabolisms to Boost Breast Cancer Immunotherapy With Microenvironment Normalization.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

Feed-Draw Printing Enables Monolithically Integrated Flexible Sensors With High Interfacial Toughness and Wide Linear Range.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

Space-Time Coding Conformal Metasurfaces for Multifrequency Beam Steering and Shaping.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

3D Printing of Magnetic Soft Materials for Functional Structures and Devices.

Advanced materials (Deerfield Beach, Fla.)·2026
Same journal

Photothermal-Activable Artificial Macrophage With Amplified Systemic Antibacterial Responses to Combat Primary and Secondary Infection.

Advanced materials (Deerfield Beach, Fla.)·2026
See all related articles

Related Experiment Video

Updated: Feb 13, 2026

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals
08:26

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals

Published on: February 24, 2012

48.3K

High-Density Stretchable Electrode Grids for Chronic Neural Recording.

Klas Tybrandt1,2, Dion Khodagholy3,4, Bernd Dielacher1

  • 1Institute for Biomedical Engineering, ETH Zurich, 8092, Zurich, Switzerland.

Advanced Materials (Deerfield Beach, Fla.)
|March 1, 2018
PubMed
Summary
This summary is machine-generated.

Researchers developed a new soft, high-density electrode grid for stable, long-term neural recording. This flexible implantable device improves brain-computer interfaces and reduces invasiveness for neurological disorder diagnosis and therapy.

Keywords:
nanowiresneural electrodesneural interfacessoft electronicsstretchable electronics

More Related Videos

Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice
10:44

Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice

Published on: July 5, 2013

21.5K
Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications
09:35

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications

Published on: October 4, 2016

10.2K

Related Experiment Videos

Last Updated: Feb 13, 2026

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals
08:26

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals

Published on: February 24, 2012

48.3K
Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice
10:44

Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice

Published on: July 5, 2013

21.5K
Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications
09:35

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications

Published on: October 4, 2016

10.2K

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Materials Science

Background:

  • Stable electrical interfacing with neural tissue is crucial for neurological disorder diagnosis, therapies, and neural signal analysis.
  • A significant challenge is the mechanical mismatch between rigid electronics and soft neural tissue, limiting long-term interface stability and performance.
  • Existing materials and fabrication methods hinder the development of soft, high-density electrode grids essential for effective neural interfacing.

Purpose of the Study:

  • To address the limitations of current neural interfaces by developing a novel soft, high-density, and stretchable electrode grid.
  • To create an implantable device capable of high-performance, long-term neural recording with preserved signal integrity.
  • To reduce the invasiveness of neural implants through a flexible and stretchable design.

Main Methods:

  • Developed a high-performance composite material using gold-coated titanium dioxide nanowires embedded in a silicone matrix.
  • Fabricated a soft, high-density, stretchable electrode grid utilizing the novel composite material.
  • Implanted the electrode grid on the surface of the cortex in freely moving rats for chronic neural recording.

Main Results:

  • The developed electrode grid successfully resolved high spatiotemporal neural signals from the rat cortex.
  • Stable neural recording quality and preserved electrode signal coherence were maintained over a 3-month implantation period.
  • The flexible and stretchable nature of the grid allowed for a minimized craniotomy, reducing surgical invasiveness.

Conclusions:

  • The novel soft, high-density, stretchable electrode grid overcomes the mechanical mismatch challenge for stable neural interfacing.
  • This technology enables high-fidelity, long-term neural recording with reduced invasiveness, offering significant potential for advancing neurological diagnostics and therapies.
  • The developed material and device technology are suitable for a broad spectrum of emerging biomedical applications, particularly in neural interfacing.