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Published on: November 13, 2019
Optimizing Drug Delivery of Small-Volume Infusions
Kelli Thoele1, Maria Piddoubny, Ryan Ednalino
1Indiana University Health, Indianapolis, Indiana (Ms Thoele, Dr Ednalino, and Mr Terry); and Thomas Jefferson University Hospital, Philadelphia, Pennsylvania (Dr Piddoubny). Kelli Thoele, MSN, RN, ACNS-BC, BMTCN®, OCN®, is a clinical nurse specialist at Indiana University Health in Indianapolis, Indiana. She is interested in evidence-based practice and safe handling of hazardous drugs. Maria Piddoubny, PharmD, BCOP, is a PGY-2 graduate of Indiana University Health in Indianapolis, Indiana, now working as a hematology/oncology patient care pharmacist at Thomas Jefferson University Hospital in Philadelphia, Pennsylvania. Her interests include chemotherapy medication safety and translational research in oncology genomics. Ryan Ednalino, PharmD, is a medication safety clinical pharmacist for Indiana University Health. He oversees medication safety initiatives across the multifacility hospital system. He serves on pharmacy and therapeutics and multiple system medication safety committees. Colin L. Terry, MS, is a biostatistician and serves as program manager for data services at Indiana University Health in Indianapolis, Indiana. He consults and collaborates on a wide variety of research projects and serves on several institutional boards as a lead statistical reviewer.
This study investigated methods for infusing residual medication from intravenous piggyback (IVPB) bags. A standard technique was recommended to minimize drug loss during IVPB administration.
Area of Science:
- Pharmacology
- Nursing Practice
- Drug Delivery Systems
Background:
- Residual medication often remains in intravenous piggyback (IVPB) administration sets and bags after infusion.
- Current practices for infusing residual IVPB medication lack standardization.
- No prior research has examined optimal techniques for residual IVPB medication administration.
Purpose of the Study:
- To identify and evaluate various ancillary techniques for administering residual medication from IVPB sets and bags.
- To quantify potential drug loss associated with different IVPB ancillary techniques.
- To recommend a standardized ancillary technique for small-volume IVPB infusions.
Main Methods:
- Qualitative assessments of existing IVPB ancillary techniques.
- Quantitative analysis to determine drug loss with each technique.
- Comparative evaluation of identified IVPB administration methods.
Main Results:
- Variability in drug recovery was observed across different IVPB ancillary techniques.
- Certain techniques resulted in significant residual drug loss.
- A specific ancillary technique demonstrated superior efficiency in drug delivery.
Conclusions:
- A standardized ancillary technique is crucial for optimizing residual medication administration in IVPB therapy.
- Implementing a recommended technique can minimize drug waste and ensure accurate dosing.
- Further research may explore the application of this technique across diverse IVPB medications and volumes.
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