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Updated: Feb 13, 2026
08:01
Stimulation of Notch Signaling in Mouse Osteoclast Precursors
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Contralateral Radiculopathy: A Kernohan-Woltman Notch-like Phenomenon
Mahdi Safdarian1, Farshid Farzaneh2, Vafa Rahimi-Movaghar1
1Sina Trauma and Surgery Research Center, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Asian Journal of Neurosurgery
|March 2, 2018
Summary
This study reports a rare case of right leg pain caused by a left-sided lumbar disc herniation. It explores potential mechanisms for this unusual contralateral radicular pain presentation.
Area of Science:
- Neurology
- Neurosurgery
- Orthopedics
Background:
- Lumbar disc herniation is a frequent cause of radiculopathy, typically presenting with ipsilateral radicular pain.
- Nerve root compression from herniated discs usually leads to symptoms on the same side as the herniation.
Observation:
- A case of right lower limb radicular pain was observed.
- The patient had a left-sided extruded L4-L5 disc herniation.
Findings:
- This presentation is unusual, as radicular pain is typically contralateral to the herniation side.
- The report reviews literature and discusses hypotheses for this contralateral phenomenon.
Implications:
- Understanding rare presentations of lumbar disc herniation is crucial for accurate diagnosis.
- This case highlights the complexity of nerve root irritation and pain referral patterns.
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