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Updated: Feb 13, 2026

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals
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Environmental Training and Synaptic Functions in Young and Old Brain: A Presynaptic Perspective

Tommaso Bonfiglio1, Matteo Vergassola1, Guendalina Olivero1

  • 1Department of Pharmacy, DIFAR, University of Genoa, Viale Cembrano 4, 16148 Genoa, Italy.

Current Medicinal Chemistry
|March 2, 2018
PubMed
Summary

Cognitive training enhances cognitive reserve in aging by reinforcing synaptic plasticity and counteracting brain impairments. This intervention impacts neurotransmitter release, potentially leading to genuine recovery of neuronal defects in aged mammals.

Keywords:
GABAYoung miceenvironmental enrichmentexocytosisglutamatenoradrenalineold mice.

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