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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Primary 'dehydration' and acute stroke: a systematic research review
Mona N Bahouth1,2, R F Gottesman3, S L Szanton4,5
1Department of Neurology, Johns Hopkins School of Medicine, 600 N. Wolfe St, Phipps 486, Baltimore, MD, 21287, USA. mbahout1@jhmi.edu.
Journal of Neurology
|March 3, 2018
Summary
Dehydration diagnosis in stroke patients lacks clear criteria, impacting early recovery. This review highlights the need for standardized diagnostic approaches and rehydration strategies to improve outcomes for stroke survivors.
Area of Science:
- Neurology
- Clinical Medicine
- Evidence-Based Practice
Background:
- Hydration status is crucial for early stroke recovery.
- Diagnosing dehydration (volume-contracted state) in stroke patients is challenging due to a lack of consensus criteria.
Purpose of the Study:
- To systematically review available evidence on the diagnosis and treatment of dehydration in stroke patients.
- To identify gaps in research regarding hydration status and stroke recovery.
Main Methods:
- Systematic literature search of PubMed, CINAHL, Cochrane, and Scopus (January 1997-March 2017).
- Inclusion of studies on hospitalized ischemic stroke patients reporting dehydration rates.
- Keywords included: hydration, dehydration, hemodilution, viscosity, volume status, and thirst.
Main Results:
- Twenty-five studies involving 8699 acute stroke patients were analyzed.
- Nineteen studies focused on diagnostic approaches to dehydration.
- Research synthesized into four categories: biological mechanisms, human measures, rehydration therapies, and outcomes.
Conclusions:
- Significant variation exists in terminology, diagnostic approaches, and treatment strategies for dehydration in stroke.
- There is a critical need for consensus on diagnostic criteria and standardized language.
- Prospective studies on rehydration strategies are needed to improve stroke outcomes.
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