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Injection Therapies for Rotator Cuff Disease.

Kenneth M Lin1, Dean Wang1, Joshua S Dines1

  • 1Sports Medicine and Shoulder Service, Hospital for Special Surgery, 535 East 70th Street, New York, NY, USA.

The Orthopedic Clinics of North America
|March 4, 2018
PubMed
Summary

Rotator cuff disease is common and treatments like injections have limited evidence. Further research into tissue deficiencies is needed for better injection therapies for rotator cuff injuries.

Keywords:
Calcific tendinitisCorticosteroidInjectionPlatelet-rich plasmaProlotherapyRotator cuffStem cellTherapy

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Area of Science:

  • Orthopedics
  • Regenerative Medicine
  • Musculoskeletal Diseases

Background:

  • Rotator cuff disease is prevalent, encompassing impingement, tendinopathy, tears, and calcific tendinitis.
  • Current injection therapies (corticosteroids, PRP, stem cells) show controversial or limited evidence.
  • A deeper understanding of rotator cuff tissue's structural and compositional deficits is lacking.

Purpose of the Study:

  • To review existing evidence for injection therapies in rotator cuff disease.
  • To highlight the need for improved understanding of rotator cuff tissue pathology.
  • To guide future development of targeted biological injection therapies.

Main Methods:

  • Literature review of injection therapies for rotator cuff conditions.
  • Analysis of current evidence regarding efficacy and limitations.
  • Identification of knowledge gaps in rotator cuff tissue biology.

Main Results:

  • Evidence supporting current injection therapies for rotator cuff disease is sparse and often contradictory.
  • Significant gaps exist in understanding the specific structural and compositional deficiencies of injured rotator cuff tissue.
  • No single injection therapy is definitively proven superior across all rotator cuff pathologies.

Conclusions:

  • Current injection therapies for rotator cuff disease lack robust supporting evidence.
  • Further research is essential to elucidate the biological needs of injured rotator cuff tissue.
  • Targeted biological therapies require a more comprehensive understanding of rotator cuff tissue composition and structure.