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Updated: Feb 13, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sleep endoscopy findings in children with persistent obstructive sleep apnea after adenotonsillectomy
Steven W Coutras1, Alexander Limjuco1, Kristin E Davis1
1Department of Otolaryngology-Head and Neck Surgery, West Virginia University, 1 Medical Center Drive, Morgantown, WV 26506, USA.
Insights
Pediatric obstructive sleep apnea (OSA) often involves multiple airway obstruction sites. Overweight children with persistent OSA show increased obstruction, particularly at the lingual tonsil and adenoid.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Respiratory Physiology
Background:
- Persistent obstructive sleep apnea (OSA) in children after adenotonsillectomy requires further investigation into obstruction patterns.
- Understanding the anatomical sites of obstruction is crucial for effective management of pediatric OSA.
- Patient weight and body mass index (BMI) may influence the location and severity of airway obstruction.
Purpose of the Study:
- To delineate the patterns of airway obstruction in children with persistent OSA.
- To examine the relationship between patient weight (BMI) and the identified sites of obstruction.
Main Methods:
- Retrospective review of pediatric DISE (Drug-Induced Sleep Endoscopy) procedures performed between 2010 and 2015.
- Analysis of polysomnography data, including Apnea-Hypopnea Index (AHI), and detailed DISE findings.
- Variables assessed included age, gender, comorbidities, and obstruction at specific upper airway levels (turbinates, adenoid, tongue base, epiglottis, etc.).
Main Results:
- Epiglottic obstruction was present in 97% of patients, frequently associated with tongue base retropositioning (73.6%) and lingual tonsil enlargement (70.5%).
- Other common obstruction sites included inferior turbinates (76.5%), adenoid (64.7%), and palate (58.8%).
- Overweight/obese children exhibited more sites of complete and partial obstruction compared to normal/underweight children, with a higher likelihood of lingual tonsil or adenoid obstruction.
Conclusions:
- Persistent pediatric OSA commonly involves multiple airway obstruction sites.
- Higher BMI in children with OSA is associated with distinct obstruction patterns, emphasizing the lingual tonsil and adenoid.
- Targeted evaluation of adenoid regrowth and lingual tonsil hypertrophy is recommended for overweight/obese children with persistent OSA.
Objectives:
Describe the patterns of obstruction in persistent pediatric OSA and their relationship with patient weight.
Study Design:
Retrospective review.
Methods:
All pediatric DISE procedures performed at a tertiary care hospital between October 2010 and October 2015 were reviewed. Patients had polysomnography after adenotonsillectomy that confirmed persistent obstructive sleep apnea (OSA). Variables included age, gender, co-morbidities, and AHI. DISE findings focused on inferior turbinates, adenoid, tongue base, epiglottis, aryepiglottic (AE) folds, arytenoids, lingual tonsil and their contributions to obstruction.
Results:
34 patients were included with mean age of 7.85 (2-16) years, mean BMI of 23.15 (13.6-44.8) and mean AHI of 6.34 (1.5-25.2) events per hour. Obstruction occurred at the level of the epiglottis in 97%, with retropositioning by tongue base (73.6%) or lingual tonsil enlargement (70.5%). Obstruction occurred at the inferior turbinates in 76.5%, the adenoid in 64.7% and the palate in 58.8%. Shortened AE folds were less often identified (15%). Multiple sites of partial or complete obstruction were found in 97% of patients. Overweight or obese patients had a mean of 3 sites of complete obstruction and 4.69 sites of partial or complete obstruction as compared to 2.33 and 4.52 in underweight or normal weight children. Overweight or obese children were more likely to have obstruction at the lingual tonsil or adenoid than normal/underweight children.
Conclusion:
Multiple sites of obstruction in persistent pediatric OSA were found. Children with higher BMIs had slightly different findings, suggesting that attention to adenoid regrowth and lingual tonsil hypertrophy is important.
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