Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Networks02:26

Protein Networks

4.6K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.6K
Protein Networks02:26

Protein Networks

2.9K
2.9K
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

3.9K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
3.9K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

10.0K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
10.0K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

3.7K
3.7K
Network Covalent Solids02:18

Network Covalent Solids

16.2K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Spatiotemporal mapping of microscale stiffness during collagen polymerization and crosslinking by optical multifrequency time-harmonic elastography.

Soft matter·2026
Same author

Field theory for optimal signal propagation in residual networks.

Physical review. E·2026
Same author

Backpropagation through space, time and the brain.

Nature communications·2025
Same author

Increased Perceptual Reliability Reduces Membrane Potential Variability in Cortical Neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2025
Same author

Building on models-a perspective for computational neuroscience.

Cerebral cortex (New York, N.Y. : 1991)·2025
Same journal

Predicting vasovagal syncope during head-up tilt test: three machine learning approaches.

Frontiers in neuroinformatics·2026
Same journal

Decoding basal ganglia motor circuit dysfunction from handwriting: a physics-informed neural signal interpretation framework for Parkinson's disease screening.

Frontiers in neuroinformatics·2026
Same journal

FUSION-AD: interpretable AI framework for risk assessment and subgroup discovery in Alzheimer's disease.

Frontiers in neuroinformatics·2026
Same journal

A 3D-printed phantom to validate subject orientation in 3D imaging and recordings.

Frontiers in neuroinformatics·2026
Same journal

IntegriLAB: a blockchain-enabled electronic lab notebook for reproducible neuroimaging research.

Frontiers in neuroinformatics·2026
Same journal

Long-range correlations in alpha-band of electroencephalogram: a nonlinear embedding and detrended fluctuation analysis.

Frontiers in neuroinformatics·2026
See all related articles

Related Experiment Video

Updated: Feb 13, 2026

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

10.9K

Extremely Scalable Spiking Neuronal Network Simulation Code: From Laptops to Exascale Computers.

Jakob Jordan1, Tammo Ippen1,2, Moritz Helias1,3

  • 1Institute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6) and JARA Institute Brain Structure-Function Relationships (INM-10), Jülich Research Centre, Jülich, Germany.

Frontiers in Neuroinformatics
|March 6, 2018
PubMed
Summary
This summary is machine-generated.

New simulation methods exploit sparsity in large-scale neuronal network models. This approach optimizes computational costs for brain-scale simulations, preparing NEST for future supercomputing advancements.

Keywords:
computational neuroscienceexascale computinglarge-scale simulationparallel computingspiking neuronal networksupercomputer

More Related Videos

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

2.2K
Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

7.6K

Related Experiment Videos

Last Updated: Feb 13, 2026

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

10.9K
Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

2.2K
Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

7.6K

Area of Science:

  • Computational Neuroscience
  • High-Performance Computing
  • Neuroscience Software Development

Background:

  • Current neuronal network simulation tools can model large networks, up to 10% of the human cortex.
  • At this scale, network connectivity becomes sparse due to connection limits per neuron.
  • Efficiently managing computational costs requires exploiting this sparsity in simulation software.

Purpose of the Study:

  • To develop and implement a computational framework that exploits sparsity in brain-scale neuronal networks.
  • To enhance simulation software for efficient execution on future high-performance computing systems.
  • To ensure performance is maintained across different system scales.

Main Methods:

  • Introduction of a two-tier connection infrastructure.
  • Development of a directed communication framework for compute nodes.
  • Implementation of the framework within the NEST simulation code.
  • Performance evaluation across various network simulation scaling scenarios.

Main Results:

  • Demonstrated feasibility of the proposed two-tier connection and communication framework.
  • The implemented technology effectively accounts for network sparsity in large-scale simulations.
  • Performance analysis confirmed the approach's suitability for post-petascale computing without compromising smaller systems.

Conclusions:

  • The new data structures and communication scheme are essential for brain-scale neural network simulations.
  • The developed framework prepares the NEST simulation kernel for future high-performance computing environments.
  • This approach ensures efficient and scalable simulations of complex neural networks.