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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Increased Risk of Ischemic Stroke during Sleep in Apneic Patients
Jin Soo Kim1, Seongheon Kim1, Seung Hwan Lee1
1Department of Neurology, Gangwon Comprehensive Stroke Center, Kangwon National University School of Medicine, Kangwon National University Hospital, Chuncheon, Korea.
Journal of Clinical Neurology (Seoul, Korea)
|March 6, 2018
Summary
Obstructive sleep apnea (OSA) symptoms preceding ischemic stroke were linked to wake-up strokes (WUS). Treating OSA may help prevent strokes, especially those occurring during sleep.
Area of Science:
- Neurology
- Sleep Medicine
- Cardiovascular Research
Background:
- Obstructive sleep apnea (OSA) is linked to increased ischemic stroke risk.
- The direct causal link between OSA and ischemic stroke remains unclear.
- Investigating OSA's role in acute ischemic stroke onset is crucial.
Purpose of the Study:
- To determine if pre-existing obstructive sleep apnea symptoms influence the occurrence of acute ischemic stroke.
- To assess the association between OSA symptoms and wake-up stroke (WUS).
Main Methods:
- A cohort of acute ischemic stroke patients was studied.
- The Berlin Questionnaire assessed pre-stroke OSA symptoms.
- Multivariate logistic regression analyzed the link between OSA symptoms and WUS.
Main Results:
- Of 260 ischemic stroke patients, 25.8% experienced WUS.
- Pre-existing witnessed or self-recognized sleep apnea was the sole significant risk factor for WUS.
- An adjusted odds ratio of 2.055 (p=0.040) confirmed this association.
Conclusions:
- Pre-existing OSA symptoms are significantly associated with WUS.
- OSA may act as both a predisposing and triggering factor for ischemic stroke.
- OSA treatment could be vital for preventing strokes, particularly sleep-onset events.
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