Related Experiment Video
Updated: Feb 13, 2026

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System
Published on: December 16, 2022
Effects of two different feeding positions on physiological characteristics and feeding performance of preterm
Burcu Aykanat Girgin1, Duygu Gözen2, Güner Karatekin3
1Faculty of Health Sciences Pediatric Nursing Department, Çankırı Karatekin University, Çankırı, Turkey.
Insights
The semielevated side-lying (ESL) position improves oxygen saturation and heart rate stability in preterm infants during bottle-feeding compared to the semielevated supine (ESU) position. This makes ESL a recommended feeding position for preterm infants.
Area of Science:
- Neonatal care
- Pediatric physiology
- Clinical nutrition
Background:
- Preterm infants often experience physiological instability during bottle-feeding.
- Current feeding positions may not optimize cardiorespiratory stability.
- Optimizing feeding positions is crucial for preterm infant well-being.
Purpose of the Study:
- To compare the effects of semielevated side-lying (ESL) and semielevated supine (ESU) positions on preterm infants' physiological status during bottle-feeding.
- To evaluate the impact of these positions on feeding performance and cardiorespiratory parameters.
Main Methods:
- A randomized controlled study involving 80 preterm infants (gestational age ≤ 31 weeks).
- Infants were randomized into ESL (n=38) and ESU (n=42) groups.
- Physiological parameters (SpO2, heart rate) and feeding performance were monitored before, during, and after feeding using pulse oximetry and video recording.
Main Results:
- Infants in the ESL group exhibited significantly higher SpO2 (96.77% ± 2.51) and lower heart rates (155.87 bpm ± 11.18) during feeding compared to the ESU group (SpO2: 93.48% ± 5.63; HR: 164.35 bpm ± 6.00).
- The ESU position was associated with greater decreases in oxygen saturation and increases in heart rate during feeding compared to baseline.
- The ESL position demonstrated better physiological stabilization during feeding.
Conclusions:
- The semielevated side-lying (ESL) position offers significant benefits for preterm infants' oxygen saturation and heart rate regulation during bottle-feeding.
- ESL promotes better physiological stability compared to the semielevated supine (ESU) position.
- The ESL position is recommended for bottle-feeding preterm infants to enhance cardiorespiratory stability and feeding performance.
Purpose:
The aim of this randomized controlled study was to determine the effect of semielevated side-lying (ESL) and semielevated supine (ESU) positions, which are used to bottle-feed preterm infants, on their physiological characteristics and feeding performance.
Design And Methods:
The sample consisted of preterm infants who were born in the 31st gestational week and below, and met the inclusion criteria. A randomization was provided in the sample group with a total of 80 infants including 38 infants in the ESL (experimental) group and 42 infants in the ESU (control) group. Both groups were compared in terms of their SpO2 values, heart rates, and feeding performances before, during, and after the feeding. The data were obtained by using a form for infant descriptive characteristics, feeding follow-up form, a Masimo Radical-7 pulse oximeter device, and a video camera.
Results:
It was determined that the infants in the ESL group had statistically significantly higher SpO2 values (ESL: 96.77 ± 2.51; ESU: 93.48 ± 5.63) and lower heart rates (ESL: 155.87 ± 11.18; ESU: 164.35 ± 6.00) during the feeding compared to the infants in the ESU group (p < .05). Besides, oxygen saturation levels of the infants in the ESU group decreased more (p < .01) and their heart rates increased more (p < .05) during the feeding than those obtained before the feeding compared to the infants in the ESL group.
Practice Implications:
The ESL position has a more positive effect on oxygen saturation and heart rate of infants and it is more effective in providing a physiological stabilization during the feeding, compared to the ESU position. According to these results, the ESL position can be recommended for preterm feeding.
Related Concept Videos
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Physiological Control of Respiration
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Physiology of Respiration II: Neurogenic Control of Respiration
Central Control
The brainstem is the primary site of central control, hosting respiratory centers:
Characteristics of Life
Trial and Error and Algorithm

