Concomitant endometrial and cervical adenocarcinoma: A case report and literature review
Mengfei Xu1, Feng Zhou, Lili Huang
1Department of Pathology Department of Obstetrics, Gynecology Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People's Republic of China.
Rationale:
Concomitant malignancy of the endometrium and cervix is extremely rare.
Patient Concerns:
A 56-year-old female presented to the Women's Hospital, School of Medicine, Zhejiang University, complaining of irregular vaginal bleeding. The human papillomavirus test (type 18/45) was positive. We performed dilation and curettage; pathology revealed moderately differentiated endometrial carcinoma exhibiting squamous differentiation. The epithelium of the cervical uterus was atypical upon biopsy.
Diagnoses:
Histological and immunochemical tests confirmed a diagnosis of endometrial carcinoma concomitant with cervical adenocarcinoma.
Interventions:
She underwent laparoscopic staging surgery.
Outcomes:
The patient fully recovered with only surgery.
Lessons:
Endometrial carcinoma concomitant with cervical adenocarcinoma is very rare. It is imperative to schedule adequate examination, and to perform careful preoperative diagnosis and appropriate treatment to minimize relapse.
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