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Updated: Feb 13, 2026

Breathing-controlled Electrical Stimulation BreEStim for Management of Neuropathic Pain and Spasticity

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Published on: January 10, 2013

[Cannabinoids for neuropathic pain management].

Lasse Østergaard Andersen¹, Thomas Peter Enggaard, Jette Højsted

¹lasse.oestergaard.andersen.01@regionh.dk.

Ugeskrift for Laeger

|March 7, 2018

Summary

Cannabis-based medicine shows limited analgesic efficacy for neuropathic pain, with minimal pain reduction observed in trials. Further research is needed due to study limitations.

Area of Science:

Neurology
Pain Management
Pharmacology

Background:

Neuropathic pain treatments often cause side effects and have limited effectiveness.
There is growing interest in cannabis-based medicine, leading to its legalization in some regions.

Purpose of the Study:

To review and evaluate the existing evidence on the efficacy of cannabinoids for treating neuropathic pain.

Main Methods:

A systematic review of seventeen clinical trials was conducted.
Trials investigating the analgesic effects of cannabis-based medicine were identified and analyzed.

Main Results:

Eight of the seventeen trials reported some analgesic efficacy for cannabis-based medicine.
The remaining trials found no significant analgesic benefits.

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Observed pain reduction was minimal across the studies.

Conclusions:

The evidence for cannabinoids in neuropathic pain is limited.
Study designs and short treatment durations restrict definitive conclusions.
Cannabis-based medicine offers minimal pain reduction for neuropathic pain currently.