Related Experiment Video
Updated: Feb 13, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Prevalence of primary open-angle glaucoma among patients with obstructive sleep apnea
Arthur H Friedlander1, Lindsay L Graves2, Tina I Chang3
1VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA; Department of Oral and Maxillofacial Surgery, School of Dentistry, University of California, Los Angeles, CA, USA; Hospital Dental Service, Ronald Reagan UCLA Medical Center, Los Angeles, CA, USA.
Objective:
Our objective was to determine primary open-angle glaucoma (POAG) prevalence among obstructive sleep apnea (OSA) patients because the perioperative environment risks further damaging the optic nerve.
Study Design:
We analyzed a "convenience sample" referred by Sleep Medicine for oral appliances because of continuous positive airway pressure intolerance. We determined the aggregate prevalence of the 3 POAG subtypes-"classic" open-angle glaucoma (COAG), normal-tension glaucoma (NTG), and open-angle glaucoma suspect (OAGS)-among the index population and compared it with that of same hospital's general population. Similarly determined were associations between OSA severity levels (apnea-hypopnea index [AHI]) and POAG subtypes.
Results:
Among the study sample of 225 patients with OSA (96.4% male; mean age 58.5 ± 12.3 years), 47 (20.9%) had POAG, with a subtype distribution of COAG: 12 (25.5%), NTG: 8 (17.0%), and OAGS: 27 (57.4%). The POAG prevalence rate among medical center's general population was 2.5%, which was significantly less (P < .00001) than among those with comorbid OSA. Severity of the breathing disorder (AHI) failed to identify a significant correlation to any POAG subtype (P > .05).
Conclusion:
The significant prevalence of POAG among OSA sufferers suggests need for preoperative consultations from an ophthalmologist to determine eye health and possibly an anesthesiologist to avoid potential vision loss.
Related Concept Videos
Sleep Apnea
The condition is more prevalent among...
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Primary Motives: Sleep, Sex, and Pain Avoidance
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...

