Automated Diagnosis of Coronary Artery Disease: A Review and Workflow

Qurat-Ul-Ain Mastoi1, Teh Ying Wah1, Ram Gopal Raj1

  • 1Faculty of Computer Science and Information Technology, University of Malaya, Kuala Lumpur 50603, Malaysia.

Insights

This review identifies optimal methods for automatic coronary artery disease (CAD) classification, aiming to streamline diagnosis. It highlights Support Vector Machine (SVM) classifiers as promising for CAD identification using noninvasive signals.

Area of Science:

  • Cardiology
  • Medical Informatics
  • Machine Learning

Background:

  • Coronary artery disease (CAD) poses significant health risks, including sudden cardiac death.
  • Current diagnostic procedures for CAD are often expensive and time-consuming.

Purpose of the Study:

  • To review state-of-the-art methods for automatic CAD classification up to 2017.
  • To identify optimal methods and classifiers for CAD identification.

Main Methods:

  • Proposed two distinct workflows (Parameter Sets A and B) for CAD classification.
  • Included preprocessing, feature extraction, feature selection, and classification stages.
  • Evaluated Support Vector Machine (SVM) as a key classifier.

Main Results:

  • Identified SVM as a promising classifier for CAD detection.
  • Highlighted the importance of proper feature extraction from noninvasive signals.
  • Established a protocol for future evaluations of automatic CAD diagnosis.

Conclusions:

  • Automatic CAD classification methods require rigorous evaluation protocols.
  • Further research is needed to optimize feature extraction from noninvasive signals for improved CAD diagnosis.

Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.2K
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
540
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
303
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
424
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
735
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
394