Related Experiment Video
Updated: Feb 13, 2026

Visualizing the Beating Heart in Drosophila
Published on: September 28, 2009
Beating-heart registration for organ-mounted robots
Nathan A Wood1, David Schwartzman2, Michael J Passineau3
1The Robotics Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.
Background:
Organ-mounted robots address the problem of beating-heart surgery by adhering to the heart, passively providing a platform that approaches zero relative motion. Because of the quasi-periodic deformation of the heart due to heartbeat and respiration, registration must address not only spatial registration but also temporal registration.
Methods:
Motion data were collected in the porcine model in vivo (N = 6). Fourier series models of heart motion were developed. By comparing registrations generated using an iterative closest-point approach at different phases of respiration, the phase corresponding to minimum registration distance is identified.
Results:
The spatiotemporal registration technique presented here reduces registration error by an average of 4.2 mm over the 6 trials, in comparison with a more simplistic static registration that merely averages out the physiological motion.
Conclusions:
An empirical metric for spatiotemporal registration of organ-mounted robots is defined and demonstrated using data from animal models in vivo.
Related Concept Videos
Beats
Anatomy of the Heart
Anatomy of the Heart
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
Levels of Organization
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
Accessory Organs
Organic Compounds

