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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
Neurological and psychiatric disorders in psoriasis
Man Amanat1,2, Mona Salehi1,2, Nima Rezaei3,4,5
1NeuroImmunology Research Association (NIRA), Universal Scientific Education and Research Network (USERN), Tehran 14194, Iran.
Psoriasis is more than a skin condition; it is a systemic disease affecting multiple organs. This review details the neurological and psychiatric disorders associated with psoriasis, highlighting its complex nature.
Area of Science:
- Dermatology
- Neurology
- Psychiatry
Background:
- Psoriasis, once viewed solely as a skin disorder, is now recognized as a systemic disease impacting various organs.
- Neurological and psychiatric conditions are increasingly identified as comorbidities in psoriasis patients.
Purpose of the Study:
- To provide a comprehensive overview of the neurological and psychiatric disorders associated with psoriasis.
- To consolidate current knowledge on the systemic implications of psoriasis.
Main Methods:
- Literature review of reported neurological and psychiatric conditions in psoriasis patients.
- Synthesis of findings from existing studies and case reports.
Main Results:
- Neurological disorders linked to psoriasis include stroke, multiple sclerosis, seizures, migraine, restless leg syndrome, Parkinson's disease, Guillain-Barré syndrome, and myasthenia gravis.
- Psychiatric manifestations encompass depression, bipolar mood disorder, anxiety, psychosis, cognitive impairment, personality disorders, sexual dysfunction, sleep disturbances, and eating disorders.
Conclusions:
- Psoriasis exhibits significant systemic involvement, extending beyond the skin to affect neurological and psychiatric health.
- Recognizing these comorbidities is crucial for comprehensive patient management and treatment strategies in psoriasis care.
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