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Spinach-based fluorescent light-up biosensors for multiplexed and label-free detection of microRNAs
Zhan-Ming Ying1, Bin Tu1, Lan Liu1
1Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China. haotang@hnu.edu.cn jianhuijiang@hnu.edu.cn.
Chemical Communications (Cambridge, England)
|March 8, 2018
Abstract:
A novel Spinach-based fluorescent light-up biosensor utilizing the T7 in vitro transcription process to generate unmodified Spinach sequences for multiplexed microRNA detection has been developed.
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