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Published on: October 27, 2014
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Recurrence of supratentorial gliomas
P N Tandon1, A K Mahapatra1, C Sarkar1
1Department of Neurosurgery, Neuroscinces Centre, All Institute of Medical Sciences. New Delhi - 110 029, India.
Neurology India
|March 8, 2018
Summary
Recurrence of supratentorial gliomas after surgery and radiotherapy could not be predicted by tumor grade or residual tumor presence. This retrospective study reviewed 200 patients with various glioma types.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Radiation Oncology
Background:
- Supratentorial gliomas are primary brain tumors requiring multimodal treatment.
- Radical surgical removal followed by radiotherapy is a standard treatment approach.
- Understanding tumor recurrence patterns is crucial for patient management.
Purpose of the Study:
- To retrospectively analyze tumor recurrence in patients with supratentorial gliomas.
- To investigate potential correlations between recurrence timing and clinicopathological factors.
Main Methods:
- Retrospective review of 200 patients with supratentorial gliomas.
- All patients underwent radical surgical tumor removal and radiotherapy.
- Follow-up ranged from one to sixteen years.
- Tumor recurrence was assessed, and data were analyzed for correlations with histological grade and postoperative CT findings.
Main Results:
- Tumor recurrence patterns were analyzed across different glioma subtypes including astrocytomas, mixed gliomas, oligodendrogliomas, malignant astrocytomas, and glioblastomas.
- The timing of recurrence could not be statistically correlated with the histological grade of the glioma.
- The presence or absence of residual tumor on postoperative CT scans did not correlate with the period of recurrence.
Conclusions:
- Recurrence timing in supratentorial gliomas is complex and not easily predicted by current standard parameters.
- Further research is needed to identify reliable predictors of recurrence.
- The study highlights challenges in diagnosis and therapy for these tumors.
