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[Characterization of the receptor for murine gamma interferon]
Giornale Di Batteriologia, Virologia Ed Immunologia
|July 1, 1985
Abstract:
Rabbits immunized with murine cells EL-4 expressing high number of interferon-gamma (IFN-gamma) receptors produce antibodies which inhibit the specific binding of murine 125I-IFN-gamma to the surface of target cells. Moreover to define the M.W. of the IFN-gamma receptor we have performed cross-linking experiments using 125I-IFN-gamma. The results obtained reveal that the IFN-gamma receptors has a M.W. of about 90-95.000 d.