In vitro activity of A-56268 (TE-031) and four other antimicrobial agents against Chlamydia trachomatis

The in vitro activity of A-56268 (TE-031), a new macrolide antibiotic, against 11 strains of Chlamydia trachomatis was determined and compared with that of four other antibiotics. A-56268 was the most active drug tested. Doxycycline, trimethoprim-sulfamethoxazole, and erythromycin had good activity but were less active in vitro than A-56268.