Related Experiment Video
Updated: Feb 13, 2026
Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
A Randomized Controlled Study Evaluating the Clinical Benefits of a Cellulose Acetate Mesh Coated with a Soft
Anne-Claire Pierrefeu-Lagrange1, Karine Mari2, Caroline Hoss3
1Plastic Reconstructive and Aesthetic Plastic Surgeon, Lyon, France.
Introduction:
Dressings are a mainstay for wound management; however, dressing adherence to the wound or periwound area can cause pain and trauma at removal. Dressing-related trauma includes skin reactions, adherence to the wound, and skin stripping. The development of atraumatic wound contact layer dressings has been a major advancement in reducing trauma.
Objective:
This study compares the benefits of a cellulose acetate mesh (CAM) coated with soft silicone versus a flexible polyamide net (FPN) coated with soft silicone.
Materials And Methods:
A multicenter, randomized controlled study was conducted in 70 patients (35 in CAM group [1 patient exclused due to not receiving treatment], 35 in the FPN group) with traumatic, postsurgical, and burn wounds. Wounds were assessed once per week for 4 weeks to measure dressing adherence to the wound bed, percent reepithelialization, and patient tolerance. All wounds were prepared according to standard of care wound management protocol at the time of assessment.
Results:
In this study, 97.06% (n = 33) of patients in the CAM group and 91.43% (n = 32) in the FPN group did not report dressing adherence during any of the assessments. Average time to complete reepithelialization was 16 days in the CAM group versus 15 days in the FPN group (P = .4958), and both products had excellent tolerance.
Conclusions:
This study demonstrated that CAM coated with a soft silicone performed as well as the FPN contact layer in minimizing dressing adherence, time to complete reepithelialization, and patient tolerance.
More Related Videos
Related Concept Videos
01:30Acute Pancreatitis II: Clinical Manifestations and Management
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
01:28Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
01:21Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
01:28Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
01:23Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...