In-hospital cardiac arrest after a rapid response team review: A matched case-control study

Joonas Tirkkonen1, Heini Huhtala2, Sanna Hoppu3

  • 1Department of Intensive Care Medicine, Tampere University Hospital and Department of Anaesthesiology and Intensive Care Medicine, Seinäjoki Central Hospital, PO Box 2000, FI-33521 Tampere, Finland.

Resuscitation
|March 10, 2018
PubMed

Insights

In-hospital cardiac arrests (IHCAs) after rapid response team (RRT) reviews are rare but have a high mortality rate. Higher National Early Warning Scores (NEWS) at the RRT review are linked to increased IHCA risk.

Area of Science:

  • Medical Research
  • Clinical Medicine
  • Cardiology

Background:

  • In-hospital cardiac arrests (IHCAs) pose a significant challenge in patient care.
  • Rapid Response Teams (RRTs) are crucial for early intervention.
  • Understanding factors leading to IHCA post-RRT review is vital for improving outcomes.

Purpose of the Study:

  • To determine the incidence and causes of IHCAs occurring after RRT reviews.
  • To identify predictors of IHCA in patients reviewed by RRTs.

Main Methods:

  • A matched case-control study was conducted at Tampere University Hospital.
  • Data collected prospectively over 5.3 years on adult patients experiencing IHCA within 48 hours post-RRT review.
  • Cases were matched 1:4 with controls who did not experience IHCA after RRT review.

Main Results:

  • 17 patients (6.3/1000 RRT reviews) experienced IHCA within 48 hours post-RRT review, with an 88% 30-day mortality.
  • Patients experiencing IHCA had higher median National Early Warning Scores (NEWS) at the end of the RRT review.
  • Higher last NEWS was the sole independent predictor of IHCA post-RRT review (OR 1.22).

Conclusions:

  • IHCA within 48 hours post-RRT review is infrequent but carries a poor prognosis.
  • Elevated NEWS at the time of RRT review is independently associated with subsequent IHCA.
  • Careful consideration is needed for patients with high NEWS remaining on general wards post-RRT review.
Abstract

Related Concept Videos

Hospitals-II00:59

Hospitals-II

Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in...
1.2K
Hospitals-I01:28

Hospitals-I

Hospitals offer medical and surgical care to the sick and injured, along with accommodation while they recover. At the same time, they also provide outpatient, emergency, psychiatric, and rehabilitation services to meet various community needs. In addition to providing medical care, hospitals also act as hubs for medical research and training. Hospitals use clinical procedures and evidence-based practice standards to deliver patient care. To deliver safe and efficient care, a nurse must stay up...
1.7K
Sign Test for Matched Pairs01:17

Sign Test for Matched Pairs

The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in...
428
Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.6K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
475