In-hospital cardiac arrest after a rapid response team review: A matched case-control study
Joonas Tirkkonen1, Heini Huhtala2, Sanna Hoppu3
1Department of Intensive Care Medicine, Tampere University Hospital and Department of Anaesthesiology and Intensive Care Medicine, Seinäjoki Central Hospital, PO Box 2000, FI-33521 Tampere, Finland.
Insights
In-hospital cardiac arrests (IHCAs) after rapid response team (RRT) reviews are rare but have a high mortality rate. Higher National Early Warning Scores (NEWS) at the RRT review are linked to increased IHCA risk.
Area of Science:
- Medical Research
- Clinical Medicine
- Cardiology
Background:
- In-hospital cardiac arrests (IHCAs) pose a significant challenge in patient care.
- Rapid Response Teams (RRTs) are crucial for early intervention.
- Understanding factors leading to IHCA post-RRT review is vital for improving outcomes.
Purpose of the Study:
- To determine the incidence and causes of IHCAs occurring after RRT reviews.
- To identify predictors of IHCA in patients reviewed by RRTs.
Main Methods:
- A matched case-control study was conducted at Tampere University Hospital.
- Data collected prospectively over 5.3 years on adult patients experiencing IHCA within 48 hours post-RRT review.
- Cases were matched 1:4 with controls who did not experience IHCA after RRT review.
Main Results:
- 17 patients (6.3/1000 RRT reviews) experienced IHCA within 48 hours post-RRT review, with an 88% 30-day mortality.
- Patients experiencing IHCA had higher median National Early Warning Scores (NEWS) at the end of the RRT review.
- Higher last NEWS was the sole independent predictor of IHCA post-RRT review (OR 1.22).
Conclusions:
- IHCA within 48 hours post-RRT review is infrequent but carries a poor prognosis.
- Elevated NEWS at the time of RRT review is independently associated with subsequent IHCA.
- Careful consideration is needed for patients with high NEWS remaining on general wards post-RRT review.
Aim:
Study the incidence and reasons behind in-hospital cardiac arrests (IHCAs) after rapid response team (RRT) reviews.
Methods:
We conducted a matched case-control study at Tampere University Hospital, Finland. Data on adult patients who were triaged to remain on general ward after first (index) RRT review without treatment limitations but who suffered an IHCA within the following 48 h were prospectively collected for 5.3 years. These cases were matched (age ±3 years, sex, surgical/medical ward, admission year) at a 1:4 ratio to controls (no ICHA after RRT review).
Results:
Of 2653 index RRT reviews, 17 patients suffered an IHCA on general ward within the 48 h after review. Their 30-day mortality rate was 88%. The incidence was 6.3/1000 index RRT reviews or 4.6/100,000 hospital admissions. Patients who suffered an IHCA within 48 h after RRT review were more likely to have a preceding ICU admission, and their median national early warning scores (NEWSs) at the end of the index RRT reviews (=last NEWSs) were higher than those of the controls. Higher last NEWS was the only factor associated with ICHA after RRT review (OR 1.22, 95% CI 1.00-1.49, p = 0.048) in a conditional multivariable regression model.
Conclusions:
IHCA within 48 h after an index RRT review on general ward is a rare event with poor prognosis. It is independently associated with higher NEWS at the end of the index RRT review. Careful consideration is stressed, when patients with high NEWS are left on ward after RRT reviews.
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