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Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
Published on: July 25, 2025
Response rate does not affect patient-reported outcome after lumbar discectomy
P Elkan1,2,3, T Lagerbäck1, H Möller1,4
1Department of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, 141 86, Stockholm, Sweden.
Quality registers provide valuable patient data, but require careful interpretation. This study found similar outcomes between a national spine registry and a prospective study for lumbar discectomy patients, suggesting registry data is reasonably representative.
Area of Science:
- Spine surgery outcomes research
- Clinical data registry analysis
- Patient-reported outcome measures (PROMs)
Background:
- Quality registers offer insights into large patient populations but may have limitations in data quality and follow-up rates compared to research studies.
- Comparing data from quality registers with prospective studies is crucial for understanding potential biases and representativeness.
- Lumbar discectomy is a common surgical procedure, making its outcome assessment in different data collection settings important.
Purpose of the Study:
- To quantify outcome differences between a national spine quality register (Swespine) and a prospective observational study (LDHS).
- To assess the representativeness of patient-reported outcome data collected through a national quality register.
- To evaluate the impact of different follow-up rates on outcome interpretation in spine surgery research.
Main Methods:
- Adult patients undergoing lumbar discectomy between 2004-2010 were analyzed from Swespine (n=7791) and LDHS (n=177).
- Follow-up rates at 1 and 2 years were significantly higher in the LDHS (98%, 99%) compared to Swespine (73%, 62%).
- Patient-reported outcomes including VAS, ODI, EQ-5D, satisfaction, and global assessment were compared at baseline and 1-2 year follow-ups.
Main Results:
- Baseline patient-reported outcomes showed minor differences between groups, within minimal clinically important differences (MCID).
- Both groups demonstrated significant improvement in outcomes post-surgery, with no substantial differences at 1 or 2 years, all within MCID.
- Complications and reoperations were similar, with the exception of a higher rate of surgical site infections in the LDHS group.
Conclusions:
- National quality registers like Swespine can provide reasonably representative patient-reported outcome data for large cohorts, even with lower response rates.
- Two-year follow-up data did not appear to add significant additional information beyond 1-year outcomes in this comparison.
- The findings support the utility of quality registers in spine surgery research, while acknowledging the need for careful interpretation.
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