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Updated: Feb 13, 2026

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface
Published on: May 1, 2020
Temperature-dependent self-assembly of a purely organic cage in water
Xujun Zheng1, Yang Zhang2, Guangcheng Wu2
1Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China. lihao2015@zju.edu.cn and Department of Chemistry, Hubei Key Lab on Organic and Polymeric, Optoelectronic Materials, Wuhan University, Wuhan 430072, P. R. China. clyang@whu.edu.cn.
Abstract:
Using a novel dynamic covalent approach relying on reversible hydrazone formation, a purely organic 3-dimensional prismatic cage was developed in water at elevated temperatures. By lowering the temperature, the hydrazone bond becomes kinetically inert. This self-assembled cage acts as an effective receptor for donor-acceptor pairs, whose interactions are weak in the absence of the cage.
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