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Associations Between Risk Factors and Overactive Bladder: A Meta-analysis.

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This study found that older age and higher body mass index increase overactive bladder (OAB) risk. Employment status, however, is linked to a reduced risk of OAB. Further research is recommended.

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Area of Science:

  • Urology
  • Public Health

Background:

  • Overactive bladder (OAB) is a common condition affecting many individuals.
  • Identifying risk factors for OAB is crucial for prevention and management strategies.

Purpose of the Study:

  • To investigate the risk factors associated with overactive bladder (OAB).

Main Methods:

  • A systematic meta-analysis was conducted using data from PubMed, Embase, and Cochrane Library databases up to May 2016.
  • Odds ratios (OR) and standard mean differences (SMDs) with 95% confidence intervals (CIs) were calculated to assess the association between risk factors and OAB.
  • Heterogeneity was evaluated using the Q and I tests.

Main Results:

  • Analysis of 28 articles revealed that increased age and body mass index were significantly associated with higher OAB risk.
  • Employment status showed a significant negative association with OAB, indicating a decreased risk.
  • Factors such as sex, education, parity, race, menopause, smoking, and alcohol consumption did not show significant differences between OAB and control groups.

Conclusions:

  • Age and body mass index are identified as significant risk factors contributing to overactive bladder.
  • Employment status appears to be a protective factor, associated with a reduced risk of OAB.
  • Further large-scale prospective studies are necessary to validate these findings and confirm the identified risk factors for OAB.