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Related Experiment Videos

Working Memory Training Improves Alcohol Users' Episodic Future Thinking: A Rate-Dependent Analysis.

Sarah E Snider1, Harshawardhan U Deshpande1, Jonathan M Lisinski1

  • 1Virginia Tech Carilion Research Institute, Virginia Polytechnic Institute and State University, Roanoke, Virginia.

Biological Psychiatry. Cognitive Neuroscience and Neuroimaging
|March 13, 2018
PubMed
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Working memory (WM) training improved cognitive tasks in individuals with alcohol dependence. This training specifically enhanced episodic future thinking (EFT) delay discounting (DD) in those with the most significant baseline deficits.

Area of Science:

  • Neuroscience
  • Psychology
  • Addiction Research

Background:

  • Episodic thinking (past/future) relies on shared neural systems, posing challenges for individuals with alcohol dependence.
  • Alcohol dependence is linked to a narrowed temporal window, increasing immediate reward valuation.
  • Working memory (WM) deficits in alcohol dependence may contribute to impaired future-oriented decision-making.

Purpose of the Study:

  • To investigate if working memory (WM) training can improve cognitive functions in alcohol-dependent individuals.
  • To assess the impact of WM training on near-transfer (novel WM) and far-transfer (delay discounting - DD, episodic future thinking - EFT DD) tasks.
  • To explore rate-dependent intervention effects, considering baseline performance variations.

Main Methods:

Keywords:
AlcoholDelay discountingEpisodic future thinkingNear-transferRate dependenceWorking memory training

Related Experiment Videos

  • Fifty alcohol-dependent individuals participated in 20 sessions of either active or sham Cogmed WM training.
  • Participants completed novel WM, delay discounting (DD), and episodic future thinking delay discounting (EFT DD) tasks pre- and post-intervention.
  • Rate-dependent analyses were employed to examine baseline performance effects on training outcomes.
  • Main Results:

    • Active WM training significantly improved performance on the near-transfer novel WM task.
    • Rate-dependent improvements were observed: individuals with lower baseline scores showed greater gains in the trained group.
    • WM training led to a rate-dependent decrease in EFT DD among those with the highest baseline EFT DD scores; no effect on DD alone was found.

    Conclusions:

    • WM training enhances near-transfer task performance in alcohol-dependent individuals.
    • WM training may improve episodic future thinking (EFT) delay discounting (DD) in a specific subset of individuals with the most impaired baseline performance.
    • Rate-dependent analysis is crucial for identifying individuals most likely to benefit from cognitive interventions.